cryogenic grinding mixer for animal feed, drugs, soils, waste, wood, textiless

Mixer Mill

  • Material feed size: ≤ 8 mm
  • Final fineness: ~ 5 µm
  • 3 different grinding modes - dry, wet or cryogenic

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The mixer mill MM 400 is a compact versatile bench-top unit, which has been developed specially for dry, wet and cryogenic grinding of small amounts of sample. 

It can mix and homogenize powders and suspensions in only a few seconds. It is also perfectly suitable for the disruption of biological cells as well as for DNA/RNA and protein extraction. With its high performance and great flexibility the mixer mill MM 400 is a unique product in the market. 

You may also be interested in the High Energy Ball Mill Emax, an entirely new type of mill for high energy input. The unique combination of high friction and impact results in extremely fine particles within the shortest amount of time.

Application Examples

alloys, animal feed, bones, ceramics, cereals, chemical products, coal, coke, drugs, electronic scrap, glass, grains, hair, minerals, oil seeds, ores, paper, plant materials, plastics, sewage sludge, soils, straw, tablets, textiles, tissue, tobacco, waste samples, wood, wool, ... 

Product Advantages

  • reproducible, efficient grinding, mixing and homogenization in seconds
  • powerful grinding by impact and friction, up to 30 Hz for up to 20 samples per run
  • 3 different grinding modes (dry, wet or cryogenic)
  • screw-top grinding jars for leak-proof grinding
  • 9 SOPs can be stored
  • wide range of accessories including various jar and ball sizes, adapter racks for single use vials and tubes, grinding tool materials, CryoKit
  • efficient cell disruption of max. 240 ml cell suspension for DNA/RNA- and protein extraction
  • isolation of bacteria from tissue in 8 x 30 ml bottles or 20 x 5 ml vials for accurate diagnosis of infections

Function Principle

The grinding jars of the MM 400 perform radial oscillations in a horizontal position. The inertia of the grinding balls causes them to impact with high energy on the sample material at the rounded ends of the grinding jars and pulverize it. Also, the movement of the grinding jars combined with the movement of the balls result in the intensive mixing of the sample. 
The degree of mixing can be increased even further by using several smaller balls. If several small balls are used (e.g. glass beads) then, for example, biological cells can be disrupted. The large frictional impact effects between the beads ensure effective cell disruption.
Applicationssize reduction, mixing, homogenization, cell disruption, cryogenic grinding
Field of applicationagriculture, biology, chemistry / plastics, construction materials, engineering / electronics, environment / recycling, food, geology / metallurgy, glass / ceramics, medicine / pharmaceuticals
Feed materialhard, medium-hard, soft, brittle, elastic, fibrous
Size reduction principleimpact, friction
Material feed size*≤ 8 mm
Final fineness*~ 5 µm
Batch size / feed quantity*max. 2 x 20ml
No. of grinding stations2
Setting of vibrational frequencydigital, 3 - 30 Hz (180 - 1800 min-1)
Typical mean grinding time30 s - 2 min
Dry grindingyes
Wet grindingyes
Cryogenic grindingyes
Cell disruption with reaction vialsyes, up to 20 x 2.0 ml
Self-centering clamping deviceyes
Type of grinding jarsscrew top design
Material of grinding toolshardened steel, stainless steel, tungsten carbide, agate, zirconium oxide, PTFE
Grinding jar sizes1.5 ml / 5 ml / 10 ml / 25 ml / 35 ml / 50ml
Setting of grinding timedigital, 10 s - 99 min
Storable SOPs9
Electrical supply data100-240 V, 50/60 Hz
Power connection1-phase
Protection codeIP 30
Power consumption150 W
W x H x D closed371 x 266 x 461 mm
Net weight~ 26 kg

*depending on feed material and instrument configuration/settings