Screening tool for laboratories reaction station

Reaction station

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The STEM Integrity 10 Reaction Station enables you to conduct 10 different reactions simultaneously, each reaction being conducted within its own cell, at its own individual temperature and stir rate.

If desired, fast heating and cooling rates can be selected, with temperature ramps of between 0.1°C/min to 5°C/min. There is also a crash function for even faster temperature changes, which is
ideal for kinetic determinations. Extreme temperature accuracy is guaranteed, with temperature stability of ± 0.5°C and a minimal set point overshoot of 0.5°C. The temperature may be maintained either through the block itself or by using a probe within each cell’s solution.

This accuracy can be maintained over a wide temperature range of -30°C to 150°C, with precise, independently controlled temperature profiles, and homogeneous sample mixing may be assured with stirring rates of between 350rpm to 1200rpm using magnetic stirrers. With working volumes of between 2ml to 25ml, the STEM Integrity 10 is an excellent screening tool for most laboratories and can also be used to establish ideal process conditions.

Key features
  • 10 individual cells in one unit
  • Individual control of temperature and stirring rate for each cell
  • Temperature range of -30°C to 150°C
  • Stirring rate of 350 rpm- 1200 rpm
  • Cell working volume of 2ml- 25ml
  • Optional attachments for refluxing, and working under vacuum or inert gas conditions
  • Optional multi-infrared probes for solubility/crystallization studies
  • Automatic microprocessor control through a touchscreen
Choice of formats

The STEM Integrity 6 and 10 Reaction Stations are available in two formats depending upon your needs:

  • Option 1: STEM Integrity 6 or10 Reaction Station as a standalone unit
  • Option 2: Clarity System, which consists of the STEM Integrity Reaction Stations, with additional solubility and crystallization evaluation apparatus and software.
Option 1Option 2
The STEM Integrity 6 or 10 unitThe Clarity System
Option 1, the STEM Integrity 6 or 10 unit by itself, is generally useful for a wide range of reactions or processes in which temperature plays a major role, regardless of the industry. Within a temperature band of -30°C to 150°C, it is applicable whether these processes are derived from the petrochemical, chemical, pharmaceutical, or food processing industries.

Different attachments may be added to these reaction cells, such as reflux heads to minimize evaporation and loss of liquid, or PTFE caps for maintaining an inert gas environment, to expand the range of uses for the STEM Integrity 10 Reaction Station.

New accessories will soon be available i.e. particle size analyzer, pH probe, UV probe, Raman probe, overhead stirrer, and specialized glassware to make Integrity a Lean “lab-in-the-box”.
One attachment that has been specifically designed for STEM Integrity is a multi-infrared (IR) probe, which is available in intrusive or non-intrusive formats. This is available as Option 2, the full Clarity System, which is finding increasing use in the pharmaceutical, petrochemical, and food industries for specialist applications. Developed in collaboration with partners at Pfizer and the Illinois Institute of Technology, the Integrity 6 or 10 STEM reaction station with integrated software are powerful tools for determining solubility and crystallization profiles. Precise heating and data collection of up to 10 reactor cells in parallel provide a rapid measurement of solubility under a range of conditions, whilst individual infrared transmission detectors allow turbidity/solubility measurements to be performed to a standardized endpoint (threshold).

It is envisaged that the full Clarity System would be a great aid in determining the solubility of drugs, the biodegradability of oils, and the crystallization characteristics of cocoa butter to name just a few potential applications.

Optimised cell design
Integrity 6 and 10
Temperature range-30°C to 150°C
Temperature ramp rate0.1°C/min to 5°C/min
Temperature accuracy± 0.5°C
Minimal set point overshoot0.5°C
Integrity 10:
Stirring rates:350 - 1200 rpm
Working volumes:2ml- 25ml
Integrity 6:
Stirring rates0 – 1300rpm
Working volumes10ml- 50ml