Biotechnology
 
    Impact ball milling

Cryogenic Grinding Mill

  • Material feed size: ≤ 8 mm
  • Final fineness: ~ 5 µm
  • 3 different grinding modes - cryogenic, dry or wet at ambient temperature

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Why buy from Geneq? - find out more

The CryoMill is tailored for cryogenic grinding

The grinding jar is continually cooled with liquid nitrogen from the integrated cooling system before and during the grinding process.

Thus the sample is embrittled and volatile components are preserved. The liquid nitrogen circulates through the system and is continually replenished from an Autofill system in the exact amount which is required to keep the temperature at -196 °C. 

Powerful impact ball milling results in perfect grinding efficiency. The Autofill system avoids direct contact with LN2 and makes cryogenic grinding very safe. Its versatility (cryogenic, wet, and dry grinding at room temperature) makes the CryoMill the ideal grinder for quantities up to 20 ml. 

Application Examples

animal feed, bones, chemical products, food, hair, oil seeds, paper, plant materials, plastics, sewage sludge, soils, tablets, textiles, tissue, waste samples, wood, wool... 

Product Advantages

  • powerful cryogenic grinding by impact and friction, up to 30 Hz
  • 3 different grinding modes (cryogenic, dry or wet at ambient temperature)
  • closed LN2-system (autofill) for enhanced safety, avoids any contact of the user with LN2
  • screw-top grinding jars for convenient, leak-proof operation
  • wide range of accessories including various LN2 feeding systems, jar and ball sizes, adapter racks, materials
  • low LN2-consumption
  • clearly structured user interface, memory for 9 SOPs
  • programmable cooling and grinding cycles (10 s to 99 min)
  • ceramic jar available

Function Principle

The grinding jar of the CryoMill performs radial oscillations in a horizontal position. The inertia of the grinding balls causes them to impact with high energy on the sample material at the rounded ends of the grinding jar and pulverize it. The grinding jar is continually cooled with liquid nitrogen from the integrated cooling system before and during the grinding process.


Applicationssize reduction, mixing, homogenization, cell disruption
Field of applicationagriculture, biology, chemistry / plastics, construction materials, engineering / electronics, environment / recycling, food, geology / metallurgy, glass / ceramics, medicine / pharmaceuticals
Feed materialhard, medium-hard, soft, brittle, elastic, fibrous
Size reduction principleimpact, friction
Material feed size*≤ 8 mm
Final fineness*~ 5 µm
Batch size / feed quantity*max. 20 ml
No. of grinding stations1
Setting of vibrational frequencydigital, 5 - 30 Hz (300 - 1800 min-1)
Typical mean grinding time10 min / 4 min (cooling / grinding)
Dry grindingyes
Wet grindingyes
Cryogenic grindingyes
Cell disruption with reaction vialsyes
Self-centering clamping deviceyes
Type of grinding jarsscrew top design
Material of grinding toolshardened steel, stainless steel, zirconium oxide, PTFE
Grinding jar sizes5 ml / 10ml / 25 ml / 35 ml / 50 ml
Autofill50 l
Setting of grinding timedigital, 30 s - 99 min
Storable SOPs9
Electrical supply data100-240 V, 50/60 Hz
Power connection1-phase
Protection codeIP 30
Power consumption260 W
W x H x D closed395 x 373 x 577 mm (D: 710 mm with exhaust tube)
Net weight~ 45 kg
StandardsCE

*depending on feed material and instrument configuration/settings