• Milk cryoscope

Milk cryoscope

The Advanced 4250 Single-Sample Cryoscope uses the industry-preferred freezing point method to precisely determine the amount of added water in milk.

The Model 4250 Cryoscope utilizes high precision thermistors to sense the sample temperature, control the degree of supercooling and freeze induction, and to measure the freezing point of the sample.

Though varying slightly by animal (cow, sheep, goat, buffalo) and diet, the freezing point of authentic samples of fresh, raw milk should be fairly consistent.

Milk becomes susceptible to both dilution and contamination as soon as it has been harvested. Milk samples found to have a freezing point warmer than established regional norms may be suspected of dilution. Furthermore, milks found to have a freezing point colder than normal may have soured or become contaminated. Combinations of both effects are quite possible and detected by freezing point.

With the Model 4250, a user can develop a freezing point range by producer, enabling storage of a “base” freezing point in the instrument memory and displaying with each sample test result the percent difference between the test result and the stored base.
The Intel® Microprocessor allows the user to recall the last 30 test results along with date and time.
The Model 4250 can be used with an optional bar code scanner –providing positive sample identification and minimizing transcription errors.


Superior Results
The Advanced 4250 offers both the International Reference and screening freezing point methods for rapid, precise, reliable results.
Versatile Operating Mode
Standard design includes m°C or m°H scale, timed plateau or plateau seeking modes, and multi-language display prompts.
Ease Of Use
Microprocessor control optimizes onboard data management capability and promotes seamless instrument operation.

Calibration of the Advanced 4250 requires no user adjustments; just follow the instrument's prompts.
Productivity Rewards
The 4250 cryoscope allows your plant to manage a premium milk supply, ensure quality products and improve your operating efficiency.
Robust Design
A frost-free cooling chamber eliminates most routine maintenance. In addition, the 4250 sample probe and stir-wire are fully accessible for easy cleaning. Other features including simple pushbutton design, multi-language capability, statistical analysis, and automated calibration make the Advanced 4250 Single-Sample Cryoscope an industry standard. 
Flexible Reporting Options
The 4250 offers a full range of data handling capabilities with an on-board printer and barcode scanner. Instrument memory provides electronic storage and retrieval of up to 30 test results.
Advanced Instruments Hot-Line Service and worldwide distributor network provide comprehensive customer service and technical support 24/7.


  • Bar code capability.
  • Electronic storage and retrieval of approximately 30 test results.
  • On-board statistical analysis (mean, standard deviation and coefficient of variation functions).
  • Improved calibration routine.
  • Data export capability.
  • Downloadable upgrades.
  • Dual range capability
  • Maintain calibration and instrument configuration settings when software is changed.
  • Multi-language capability
  • Reduced instrument footprint.
  • New, on board printer.
  • Vertical printout.


  • Permit entry of sample and operator ID and minimize transcription errors.
  • Improved information retrieval.
  • Convenient data analysis.
  • Minimize calibration frequency.
  • Ability to link to external computer.
  • Easily keep instrument software current.
  • Versatility to test different product types.
  • Seamless operation of instrument following upgrade.
  • Utilize instrument in native language
  • Maximize available bench space.
  • Robust, reliable thermal printer.
  • Convenient visibility of printout.
Sample Volume 2 or 2.5 mL
Test Time Approximately 90 seconds in the 30-second timed mode
Sample Capacity Single Sample
Units -m°C or -m°H
Resolution 1 m°C or m°H
Range 0 to 1000 m°C or m°H
Communications On-board printer, DTE RS-232 serial port, and optional barcode scanner
Performance at Reference Conditions1
Linearity Less than ±0.5% from a straight line
Repeatability ±2 m°C or m°H (1 S.D.)
Drift Less than 1 m°C or m°H per month
Performance Over Operating Conditions
Temperature Effects Less than 1 m°C or m°H per 5°C (9°F) ambient temperature change
Operating Conditions
Temperature 18 to 35°C (64 to 95°F)
Humidity 5 to 80% relative humidity, (non-condensing)
Storage Temperature -40 to +45°C (-40 to +113°F)
Electrical Voltage 100 to 130 VAC (50/60 Hz) or 200 to 250 VAC (50/60 Hz)
Power Consumption 150 Watts
Dimensions 16.0” H x 13.0” W x 18.0” D
40.6 cm x 33.0 cm x 45.7 cm
Net Weight 28.0 lbs. (12.7 kg)
Shipping Weight 39.0 lbs. (17.7 kg)
One year limited warranty on workmanship and all parts except glass, plastic, and parts warranted by their makers